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Current progresses on nanodelivery systems for the treatment of neuropsychiatric diseases: Alzheimer’s and Schizophrenia

2013Journal article Restricted access
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dc.contributor.authorSilva, Ana Catarina
dc.contributor.authorGonzález-Mira, E.
dc.contributor.authorLobo, J.M. Sousa
dc.contributor.authorAmaral, M.H.
dc.date.accessioned2021-04-30T10:27:45Z
dc.date.available2021-04-30T10:27:45Z
dc.date.issued2013
dc.description.abstractCurrently Alzheimer's disease and schizophrenia are both well-established neuropsychiatric diseases. Nonetheless, the treatment of these disorders is not unanimous and fully effective. As a consequence, several approaches have been studied to improve patient's conditions. In this context, the development of new drug nanodelivery systems to increase drug bioavailability and reduce adverse effects has been claimed as a good option. Among these systems we focus on the ones that seem to be most promising, such as lipidbased systems (e.g. liposomes, nanoemulsions and lipid nanoparticles), drug nanocrystals, polymeric nanoparticles and micelles. Moreover, the application of these systems by means of alternative administration routes is also discussed. Regardless of the satisfactory results and the associated progresses that have been done in the last years, more studies are required to quickly licence the application of drug nanodelivery systems in human medicines.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.2174/138161281941131219123329pt_PT
dc.identifier.issn1381-6128
dc.identifier.urihttp://hdl.handle.net/10284/9840
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBentham Science Publisherspt_PT
dc.subjectAlzheimer'spt_PT
dc.subjectSchizophreniapt_PT
dc.subjectLiposomespt_PT
dc.subjectNanoemulsionspt_PT
dc.subjectLipid nanoparticlespt_PT
dc.subjectDrug nanocrystalspt_PT
dc.subjectPolymeric nanoparticlespt_PT
dc.subjectMicellespt_PT
dc.titleCurrent progresses on nanodelivery systems for the treatment of neuropsychiatric diseases: Alzheimer’s and Schizophreniapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleCurrent Pharmaceutical Designpt_PT
oaire.citation.volume19pt_PT
person.familyNameSilva
person.givenNameAna Catarina
person.identifier953153
person.identifier.ciencia-id5C1D-ED22-0D64
person.identifier.orcid0000-0001-6923-0232
person.identifier.ridF-1875-2017
person.identifier.scopus-author-id57028697500
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication67e7f707-32ec-444a-a20d-a17f8e6e7c21
relation.isAuthorOfPublication.latestForDiscovery67e7f707-32ec-444a-a20d-a17f8e6e7c21

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