Bacteriophage Phi 6 as surrogate and human-harmless viruses to study anti-SARS-CoV-2 approaches

Barros, Joana; Monteiro, Fernando; Ferraz, Maria Pia

http://hdl.handle.net/10284/9718

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Authors

Barros, Joana

Monteiro, Fernando

Ferraz, Maria Pia

Abstract(s)

Given safety challenges in conducting laboratory work with highly infectious human coronaviruses (pathogenicity, genetic mutations rate, biosafety level 3 and 4 requirements), many researchers have valued the potential of bacteriophages as appropriate viral surrogate to measure humans enveloped virus’ survival, transfer and removal. The use of phage Φ6 seems to be useful as coronavirus surrogate to assess the effectiveness of anti-SARS-CoV-2 approaches, providing important insights concerning COVID-19 pandemic and human public health.