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Osseointegration and cell response on titanium implant surface treatments

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Introdução: A osteointegração de um implante é essencial para garantir êxito clínico. Vários tratamentos de superfície foram introduzidos para melhorar a osseointegração e a biocompatibilidade de um implante. Objectivos: O objectivo de esta revisão bibliográfica é explorar as diferentes propriedades de Titanio e como á modifica-las, depois de introduzir um implante de Titanio num tecido de osso vivo, a osteointrgração, a resposta celular e a biocompatibilidade do implante podem ser afectadas. Materiais e métodos: Para esta revisão bibliográfica, 96 artigos foram usados, tombados das seguintes bases de dados: Pubmed, Science direct and Scielo. Através das seguintes palavras chave: "Surface treatments", "Titanium dental implants", "osseointegration", "anodization", "anodic oxidation", "plasma spraying", "HA coatings", "hydroxyapatite coatings", "acid etching", "grit blasting”, “tribocorrosion" AND “biotribocorrosion”. Conclusão: Foi concluído que a superfície ideal deve presentear uma rugosidade de superfície e 1-2μm, exibir aumentada hidrofilicidade e apresentar uma grossa camada de óxido. Deve também carecer de contaminastes citototòxicos a fim de promover um ambiente biológico favorável e finalmente, foi demonstrado que uma carga negativa promove resposta celular.
Introduction: The osseointegration of an implant is essential in order to achieve clinical success. Various surface treatments have been introduced in order to achieve a better osseointegration and biocompatibility of the implant. Objectives: The objective of this review was to explore the different properties of titanium and how by changing them, after a titanium implant being introduced to living bone tissue, osseointegration, cellular response and biocompatibility of the implant can be affected. By this it can be understood what to look for in an implant surface, concluding to the ideal surface characteristics a Ti implant should possess. Materials and Methods: For this review, they were used 96 articles, retrieved from the following search engines: Pubmed, Science direct and Scielo. Through the following key words: "Surface treatments", "Titanium dental implants", "osseointegration", "anodization", "anodic oxidation", "plasma spraying", "HA coatings", "hydroxyapatite coatings", "acid etching", "grit blasting”, “tribocorrosion" AND “biotribocorrosion”. Conclusion: It was concluded that the ideal surface should present a surface roughness of 1-2μm, have increased hydrophilicity and present a thick oxide layer. It should also lack of any cytotoxic contaminants in order to promote a favorable biologic environment and finally, a negative charge has been shown to promote cell response.

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Surface treatments Titanium dental implants Osseointegration Anodization Anodic oxidation Plasma spraying HA coatings Hydroxyapatite coatings Acid etching Grit blasting Tribocorrosion Biotribocorrosion

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