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Abstract(s)
Uma das questões centrais da ortodontia moderna é: como as descobertas na área da genética afetarão diretamente conceitos e abordagens no tratamento ortodôntico e de que forma os fatores genómicos e epigenéticos podem ser manipulados e introduzidos no tratamento individual de cada paciente. O objetivo deste trabalho é demonstrar a importância da genética na previsão do crescimento mandibular. Esta dissertação é de índole teórica, estando desta forma isenta de qualquer tipo de trabalho prático experimental. Trata-se de uma revisão sistemática de trabalhos que estudaram o tema.
A ortodontia baseada no genoma usa a informação genética para melhorar o diagnóstico e tratamento de distúrbios dentários e deformidades dentofaciais. Nos últimos 20 anos houve uma convergência de princípios e conceitos entre a genética e a ortodontia que levará a um avanço significativo dos tratamentos ortodonticos, contudo a sua aplicação prática não será imediata.
The central question in orthodontics in this millennium is: how discoveries in the field of genetics will directly affect concepts and approaches in orthodontic treatment and how genomic and epigenetic factors can be manipulated and introduced into the individual treatment of each patient. The aim of this study is to demonstrate the importance of genetics in the prediction of mandibular growth. This dissertation is of a theoretical nature, being thus exempt of any type of practical experimental work. This is a systematic review of papers that have studied the theme. Genome based orthodontics uses genetic information to improve the diagnosis and treatment of dental disorders and dentofacial deformities. In the last 20 years there has been a convergence of principles and concepts between genetics and orthodontics that will lead to a significant advance in orthodontic treatments, however, its practical application will not be immediate.
The central question in orthodontics in this millennium is: how discoveries in the field of genetics will directly affect concepts and approaches in orthodontic treatment and how genomic and epigenetic factors can be manipulated and introduced into the individual treatment of each patient. The aim of this study is to demonstrate the importance of genetics in the prediction of mandibular growth. This dissertation is of a theoretical nature, being thus exempt of any type of practical experimental work. This is a systematic review of papers that have studied the theme. Genome based orthodontics uses genetic information to improve the diagnosis and treatment of dental disorders and dentofacial deformities. In the last 20 years there has been a convergence of principles and concepts between genetics and orthodontics that will lead to a significant advance in orthodontic treatments, however, its practical application will not be immediate.
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Keywords
Prognatismo mandibular Genoma Saliva Biossensores Mandibular prognathism Genome Saliva Biosensors
