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Publication
Problemas respiratórios e relação com a cavidade oral na SARS-CoV-2: revisão narrativa
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Advisor(s)
Abstract(s)
A doença coronavírus 2019 (COVID-19), provocada pelo vírus SARS-CoV-2, é o problema de saúde mais urgente e preocupante em todo o mundo. Enquanto a maioria dos casos resulta em sintomas leves, alguns casos evoluem para pneumonia grave e falência de múltiplos órgãos com a morte do paciente. Os mecanismos de entrada do SARS-CoV-2 nas células são conhecidos e o agravamento dos sintomas em alguns pacientes tem produzido numerosos estudos que relacionam a COVID-19 às doenças crónicas, dentre essas, a periodontite.
O objetivo desse trabalho foi realizar uma revisão da literatura sobre como as células da cavidade oral atuam como porta de entrada da infeção viral e a participação de patologias bucais no agravamento dos quadros respiratórios da COVID-19.
Por ser a COVID- 19 uma doença recente, são necessárias futuras investigações, entretanto as evidências nos permitem concluir que os cuidados bucais preventivos, nomeadamente os periodontais, podem favorecer a não-evolução para os sintomas respiratórios graves.
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 virus, is the most pressing and worrisome health problem worldwide. While most cases result in mild symptoms, some cases progress to severe pneumonia and multi organ failure with the death of the patient. The entry mechanisms of SARS-CoV-2 into cells are known and the aggravation of symptoms a few patients has produced numerous studies linking COVID-19 to chronic diseases including periodontitis. The purpose of this study was to review the literature on how cells in the oral cavity act as a gateway for viral infection and the participation of oral pathologies to the aggravation of respiratory conditions of COVID-19. As COVID-19 is a recent disease, future investigations are needed, however the evidence allows us to conclude that preventive oral care, particularly periodontal care, can favor the non- evolution to severe respiratory symptoms.
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 virus, is the most pressing and worrisome health problem worldwide. While most cases result in mild symptoms, some cases progress to severe pneumonia and multi organ failure with the death of the patient. The entry mechanisms of SARS-CoV-2 into cells are known and the aggravation of symptoms a few patients has produced numerous studies linking COVID-19 to chronic diseases including periodontitis. The purpose of this study was to review the literature on how cells in the oral cavity act as a gateway for viral infection and the participation of oral pathologies to the aggravation of respiratory conditions of COVID-19. As COVID-19 is a recent disease, future investigations are needed, however the evidence allows us to conclude that preventive oral care, particularly periodontal care, can favor the non- evolution to severe respiratory symptoms.
Description
Keywords
SARS-CoV-2 Cavidade oral Periodontite Doença periodontal Pneumonia Oral cavity Periodontitis Periodontal disease