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Diagnóstico de doença celíaca através da saliva
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_25969 | 228.55 KB | Adobe PDF |
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Abstract(s)
A doença celíaca é uma patologia baseada numa intolerância à ingestão de glúten estando subjacente a uma predisposição genética com dificil diagnóstico. Esta patologia tem inúmeras características clínicas, nomeadamente diarreira crónica, cansaço, distensão abdominal, vómitos, perda de peso, fraqueza muscular, fezes soltas e severa atrofia da mucosa do intestino delgado. Existem vários tipos de meios de diagnóstico para a doença celíaca, como, serologia e biópsia duodenal, sendo a última o meio mais importante de diagnóstico.
O objectivo desta revisão narrativa da literatura consistiu no possível diagnóstico desta patologia através da saliva usando anticorpos, sendo este um método menos invasivo e rápido podendo fazer um diagnóstico inicial de triagem.
Celiac disease is a pathology based on an intolerance to glutin intake and underlies a genetic predisposition with difficult diagnosis. This pathology has numerous clinical features, such as chronic diarrhea, tiredness, abdominal distension, vomiting, weight loss, muscle weakness, loose stools and severe mucosal atrophy of the small intestine. There are several types of diagnostic tools for celiac disease, such as serology and duodenal biopsy, the last one being the most important diagnostic tool. The objective of this narrative review of the literature consisted in the possible diagnosis of this pathology through saliva using antibodies, which is a less invasive and fast method and can make an initial diagnosis of screening.
Celiac disease is a pathology based on an intolerance to glutin intake and underlies a genetic predisposition with difficult diagnosis. This pathology has numerous clinical features, such as chronic diarrhea, tiredness, abdominal distension, vomiting, weight loss, muscle weakness, loose stools and severe mucosal atrophy of the small intestine. There are several types of diagnostic tools for celiac disease, such as serology and duodenal biopsy, the last one being the most important diagnostic tool. The objective of this narrative review of the literature consisted in the possible diagnosis of this pathology through saliva using antibodies, which is a less invasive and fast method and can make an initial diagnosis of screening.
Description
Keywords
Doença celíaca Saúde oral Diagnóstico salivar Medicina oral Celiac disease Oral health Diagnosis saliva Oral medicine