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Publication
As vitaminas C e E no desenvolvimento da doença periodontal: revisão narrativa
| Name: | Description: | Size: | Format: | |
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| 36345 | 307.85 KB | Adobe PDF |
Advisor(s)
Abstract(s)
Esta revisão fornece uma análise abrangente do papel das vitaminas C e E no desenvolvimento da doença periodontal, nomeadamente no combate ao stress oxidativo e à inflamação resultante.
Um dos fatores agravantes no desenvolvimento do processo inflamatório é o stress oxidativo. No decorrer da doença periodontal, o equilibro fisiológico do organismo de reduzir espécies reativas de oxigénio é ultrapassado e o seu excesso atua como promotor para a inflamação local contribuindo para a redução do tecido de suporte periodontal remanescente.
Neste contexto, enzimas antioxidantes são a primeira linha de defesa contra a excessiva acumulação de espécies reativas de oxigénio, no entanto antioxidantes exógenos, como a vitamina C e E providenciam um suporte importante na manutenção dos níveis de espécies reativas de oxigénio. Estas vitaminas, que possuem múltiplas e importantes funções biológicas, podem atuar em sinergia com enzimas endógenas reduzindo os efeitos do stress oxidativo.
This review provides a comprehensive analysis of the role of vitamins C and E in the development of periodontal disease, particularly in combating oxidative stress and the resulting inflammation. One of the aggravating factors in the development of the inflammatory process is oxidative stress. During the course of periodontal disease, the body's physiological balance of reducing reactive oxygen species is exceeded and its excess acts as a promoter for local inflammation, contributing to the reduction of the remaining periodontal support tissue. In this context, antioxidant enzymes are the first line of defense against the excessive accumulation of reactive oxygen species, but exogenous antioxidants such as vitamin C and E provide important support in maintaining levels of reactive oxygen species. These vitamins, which have multiple and important biological functions, can act in synergy with endogenous enzymes to reduce the effects of oxidative stress.
This review provides a comprehensive analysis of the role of vitamins C and E in the development of periodontal disease, particularly in combating oxidative stress and the resulting inflammation. One of the aggravating factors in the development of the inflammatory process is oxidative stress. During the course of periodontal disease, the body's physiological balance of reducing reactive oxygen species is exceeded and its excess acts as a promoter for local inflammation, contributing to the reduction of the remaining periodontal support tissue. In this context, antioxidant enzymes are the first line of defense against the excessive accumulation of reactive oxygen species, but exogenous antioxidants such as vitamin C and E provide important support in maintaining levels of reactive oxygen species. These vitamins, which have multiple and important biological functions, can act in synergy with endogenous enzymes to reduce the effects of oxidative stress.
Description
Keywords
Doença periodontal Antioxidantes Vitamina C Vitamina E Periodontal disease Antioxidants Vitamin C Vitamin E