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The main potentialities of resveratrol for drug delivery systems

2015Journal article Open access
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dc.contributor.authorRuivo, Joana
dc.contributor.authorFrancisco, Cátia
dc.contributor.authorOliveira, Rita
dc.contributor.authorFigueiras, Ana
dc.date.accessioned2022-01-26T12:25:18Z
dc.date.available2022-01-26T12:25:18Z
dc.date.issued2015
dc.description.abstractResveratrol (RSV), a natural polyphenol found in grapes, was found to be effective in the prevention and therapy of several diseases, however, it does have unfavourable physicochemical properties. In this context, an increasing number of studies have aimed at developing novel therapeutic systems for its delivery to overcome these disadvantages. This review focuses on the mechanisms of action and therapeutic applications. Finally, it also describes some tested formulations for RSV administration, controlled release and targeting, developed with the purpose of increasing RSV bioavailability.pt_PT
dc.description.abstractO resveratrol (RSV) é um polifenol natural encontrado nas uvas, que se mostrou eficaz na prevenção e terapia de várias doenças. No entanto, apresenta propriedades físico-químicas desfavoráveis. Neste contexto, um número cada vez maior de estudos visando ao desenvolvimento de novos sistemas terapêuticos para a sua liberação vem sendo desenvolvido no sentido de ultrapassar estas desvantagens. Esta revisão discorre sobre os mecanismos de ação e aplicações terapêuticas do RSV. Finalmente, são abordadas algumas formulações de liberação controlada e vetorizada, testadas para administração do RSV, desenvolvidas com a finalidade de aumentar a biodisponibilidade do RSV.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1590/S1984-82502015000300002pt_PT
dc.identifier.issn2175-9790
dc.identifier.urihttp://hdl.handle.net/10284/10665
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFaculty of Pharmaceutical Sciences of the University of São Paulopt_PT
dc.subjectNutraceuticalspt_PT
dc.subjectNatural polyphenolspt_PT
dc.subjectResveratrol/mechanisms of actionpt_PT
dc.subjectResveratrol/ therapeutic applicationspt_PT
dc.subjectResveratrol/delivery systemspt_PT
dc.subjectNutracêuticospt_PT
dc.subjectPolifenóis naturaispt_PT
dc.subjectResveratrol/mecanismo de açãopt_PT
dc.subjectResveratrol/aplicações terapêuticaspt_PT
dc.subjectResveratrol/sistemas de liberaçãopt_PT
dc.titleThe main potentialities of resveratrol for drug delivery systemspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage513pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage499pt_PT
oaire.citation.titleBrazilian Journal of Pharmaceutical Sciencespt_PT
oaire.citation.volume51pt_PT
person.familyNameOliveira
person.givenNameRita
person.identifier.ciencia-id371C-F327-9C9C
person.identifier.orcid0000-0003-0258-9472
person.identifier.scopus-author-id55974811800
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationeec36871-71b7-4563-b864-3595628f7194
relation.isAuthorOfPublication.latestForDiscoveryeec36871-71b7-4563-b864-3595628f7194

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