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Immunology of dental caries: a narrative review
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 34967 | 332.15 KB | Adobe PDF |
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Abstract(s)
A cárie dentária é uma das doenças infeciosas mais prevalentes no mundo moderno. Segundo a OMS, a cárie afeta entre 60 e 90% das crianças do mundo, tornando-se a terceira doença mais prevalente no mundo. Bactérias cariogênicas orais podem infiltrar-se no biofilme dental e, posteriormente, emergir para causar doenças em circunstâncias ambientais adequadas. A resposta imunológica do hospedeiro a esta infeção, bem como a forma como o desenvolvimento e as deficiências do sistema imunológico afetam esta resposta, podem, portanto, nos esclarecer sobre uma estratégia de tratamento potencialmente viável. Como a periodontite e a cárie são doenças infeciosas da cavidade oral nas quais os biofilmes orais estão envolvidos, é fundamental entender as características únicas desses biofilmes para avaliar a terapia de curto, médio e longo prazo.
Caries of the teeth are one of the most prevalent infectious illnesses in the modern world. According to the WHO, caries affects between 60 and 90% of the world's children, making it the third most prevalent illness worldwide. Oral cariogenic bacteria may infiltrate the dental biofilm and subsequently emerge to cause illness under suitable environmental circumstances. The host immunological response to this infection, as well as how the immune system's development and deficiencies impact this response, might therefore enlighten us about a potentially viable treatment strategy. As periodontitis and caries are infectious illnesses of the oral cavity in which oral biofilms are involved, it is critical to understand the unique features of these biofilms to evaluate short-, medium-, and long-term therapy.
Caries of the teeth are one of the most prevalent infectious illnesses in the modern world. According to the WHO, caries affects between 60 and 90% of the world's children, making it the third most prevalent illness worldwide. Oral cariogenic bacteria may infiltrate the dental biofilm and subsequently emerge to cause illness under suitable environmental circumstances. The host immunological response to this infection, as well as how the immune system's development and deficiencies impact this response, might therefore enlighten us about a potentially viable treatment strategy. As periodontitis and caries are infectious illnesses of the oral cavity in which oral biofilms are involved, it is critical to understand the unique features of these biofilms to evaluate short-, medium-, and long-term therapy.
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Keywords
Imunologia Cárie Biofilme Microbioma Infeção Placa bacteriana Sistema imunológico Immunology Caries Biofilm Microbiome Infection Bacterial plaque Immune response