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Influência do HPV na saúde oral e a perspetiva da Medicina Dentária: estado da arte
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_26175 | 3.13 MB | Adobe PDF |
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Advisor(s)
Abstract(s)
A prevalência de HPV no cancro da orofaringe está a aumentar, contudo, cancros HPV
positivos tm bom prognóstico, respondem bem à terapêutica e normalmente aparecem
em zonas como a base da língua, amígdalas e palato mole. É importante conhecer este
vírus e quais as lesões benignas, pré-malignas e malignas que este pode induzir.
Este vírus possui subtipos de alto ou de baixo risco e estão associados a lesões benignas
ou malignas, sendo que o HPV 16 é o de maior perigo e as suas oncoproteínas uma das
responsáveis pela transformação maligna das células do hospedeiro.
Um maior conhecimento destas lesões e a sua distinção irá permitir um diagnóstico
precoce, melhorando o prognóstico, assim como a educação para a saúde oral e
promoção do auto exame devem ser prática corrente na consulta de medicina dentária.
Das 60 referências pesquisadas, incluíndo livros, artigos e revistas, os critérios de
inclusão utilizados na seleção dos artigos foram: publicações compreendidas entre o ano
2010 a 2017, artigos escritos em português e inglês e, de acordo com a pertinência e
enquadramento da informação recolhida, foram efectivamente utilizados 42 referências
nesta dissertação.
The prevalence of HPV in oropharyngeal cancer is increasing, however, HPV positive cancer has a good prognosis, respond well to therapy, and usually appear in areas such as the base of the tongue, tonsils, and soft palate. It is important to know this virus and what benign, pre-malignant and malignant lesions it can induce. This virus has high or low risk subtypes and is associated with benign or malignant lesions, with HPV 16 being the most dangerous and its oncoproteins one off the responsible for malignant transformation of host cells. Further knowledge of these lesions and their distinction will allow an early diagnosis, improving prognosis, as well as oral health education and self-examination promotion should be current practice in the dental clinic. From the 60 references surveyed, including books, articles and journals, the inclusion criteria used in the selection of articles were: publications between 2010 and 2017 e articles written in Portuguese and English. According to consultation and classification of the information collected, 42 references were actually used in this dissertation.
The prevalence of HPV in oropharyngeal cancer is increasing, however, HPV positive cancer has a good prognosis, respond well to therapy, and usually appear in areas such as the base of the tongue, tonsils, and soft palate. It is important to know this virus and what benign, pre-malignant and malignant lesions it can induce. This virus has high or low risk subtypes and is associated with benign or malignant lesions, with HPV 16 being the most dangerous and its oncoproteins one off the responsible for malignant transformation of host cells. Further knowledge of these lesions and their distinction will allow an early diagnosis, improving prognosis, as well as oral health education and self-examination promotion should be current practice in the dental clinic. From the 60 references surveyed, including books, articles and journals, the inclusion criteria used in the selection of articles were: publications between 2010 and 2017 e articles written in Portuguese and English. According to consultation and classification of the information collected, 42 references were actually used in this dissertation.
Description
Keywords
HPV cancro oral Epidemiologia do cancro oral e HPV HPV proteinas oncogénicas HPV lesões HPV diagnóstico HPV vacinação oral HPV cancro cabeça e pescoço HPV papel do dentista HPV oral cancer Epidemiology oral cancer and HPV HPV oncogene proteins HPV oral lesions HPV diagnostic HPV oral vaccination HPV head and neck cancer HPV dentist role