Repository logo
 
Publication

Delivery systems for biopharmaceuticals. Part II: liposomes, micelles, microemulsions and dendrimers

2015Journal article Restricted access
Simple item page
dc.contributor.authorSilva, Ana Catarina
dc.contributor.authorLopes, Carla Martins
dc.contributor.authorLobo, J.M. Sousa
dc.contributor.authorAmaral, M.H.
dc.date.accessioned2020-09-29T16:35:36Z
dc.date.available2020-09-29T16:35:36Z
dc.date.issued2015
dc.date.updated2020-07-24T15:28:45Z
dc.description.abstractBiopharmaceuticals are a generation of drugs that include peptides, proteins, nucleic acids and cell products. According to their particular molecular characteristics (e.g. high molecular size, susceptibility to enzymatic activity), these products present some limitations for administration and usually parenteral routes are the only option. To avoid these limitations, different colloidal carriers (e.g. liposomes, micelles, microemulsions and dendrimers) have been proposed to improve biopharmaceuticals delivery. Liposomes are promising drug delivery systems, despite some limitations have been reported (e.g. in vivo failure, poor long-term stability and low transfection efficiency), and only a limited number of formulations have reached the market. Micelles and microemulsions require more studies to exclude some of the observed drawbacks and guarantee their potential for use in clinic. According to their peculiar structures, dendrimers have been showing good results for nucleic acids delivery and a great development of these systems during next years is expected. This is the Part II of two review articles, which provides the state of the art of biopharmaceuticals delivery systems. Part II deals with liposomes, micelles, microemulsions and dendrimers.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.2174/1389201016666150817094637pt_PT
dc.identifier.eid2-s2.0-84942155383
dc.identifier.eid2-s2.0-84942096153
dc.identifier.issn1389-2010
dc.identifier.slugcv-prod-337021
dc.identifier.urihttp://hdl.handle.net/10284/9013
dc.language.isoengpt_PT
dc.publisherBentham Science Publisherspt_PT
dc.subjectBiopharmaceuticalspt_PT
dc.subjectProteinspt_PT
dc.subjectPeptidespt_PT
dc.subjectNucleic acidspt_PT
dc.subjectLiposomespt_PT
dc.subjectMicellespt_PT
dc.subjectMicroemulsionspt_PT
dc.subjectDendrimerspt_PT
dc.titleDelivery systems for biopharmaceuticals. Part II: liposomes, micelles, microemulsions and dendrimerspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage965pt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPage955pt_PT
oaire.citation.titleCurrent Pharmaceutical Biotechnologypt_PT
oaire.citation.volume16pt_PT
person.familyNameSilva
person.familyNameLopes
person.givenNameAna Catarina
person.givenNameCarla
person.identifier953153
person.identifier.ciencia-id5C1D-ED22-0D64
person.identifier.ciencia-id901D-160C-633E
person.identifier.orcid0000-0001-6923-0232
person.identifier.orcid0000-0001-5080-032X
person.identifier.ridF-1875-2017
person.identifier.ridM-4689-2016
person.identifier.scopus-author-id57028697500
person.identifier.scopus-author-id26649517700
rcaap.cv.cienciaid901D-160C-633E | Carla Martins Lopes
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication67e7f707-32ec-444a-a20d-a17f8e6e7c21
relation.isAuthorOfPublicationd2a48cfe-9258-4916-99be-bbcb710f6605
relation.isAuthorOfPublication.latestForDiscovery67e7f707-32ec-444a-a20d-a17f8e6e7c21

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Current_Pharmaceutical_Biotechnology___Part_II___2015.pdf
Size:
805.3 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.64 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

FCS (DCF) - Artigos em Revistas Científicas Internacionais com Arbitragem Científica