Browsing by Author "Felino, Eurico Melo"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
- Sindrome de sjögren: da imunologia à terapia genéticaPublication . Silva, António Pedro; Felino, Eurico MeloSjögren`s syndrome (SS) is a chronic inflammatory disease with major immunological features that include infiltration of salivary and lacrimal glands by CD4+ T cells and B cells, the presence of autoantibodies to nucleoproteins and its genetic predisposition linked to the HLA region. It`s diagnosis can be made using different criteria approved by WHO. Recent advances in the field of genetic therapy opens new perspectives for the treatment of SS – the use of genes encoding for anti-inflamatory cytokines is being studied.