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ImunonutriĆ§Ć£o em doentes com cancro gastrointestinal

2013Bachelor thesis Open access
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dc.contributor.advisorSoares, Sandra
dc.contributor.authorMoreira, Ricardo Filipe Silva
dc.date.accessioned2014-07-09T07:48:15Z
dc.date.available2014-07-09T07:48:15Z
dc.date.issued2013
dc.descriptionTrabalho Complementar apresentado Ć  Universidade Fernando Pessoa como parte dos requisitos para obtenĆ§Ć£o do grau de licenciado em CiĆŖncias da NutriĆ§Ć£opor
dc.description.abstractObjetivo: Fazer uma breve revisĆ£o da literatura sobre a importĆ¢ncia da nutriĆ§Ć£o artificial, nomeadamente a imunonutriĆ§Ć£o, por via entĆ©rica, em doentes com cancro gastrointestinal, sujeitos ou nĆ£o a cirurgia. Metodologia: Foi realizada uma pesquisa na base de dados da National Library of Medicine PUBMed-Medline e B-on, entre Abril e Outubro de 2013, utilizando-se os termos de pesquisa: ā€œimmunonutrition in gastrointestinal cancer surgeryā€, ā€œenteral immunonutrition gastrointestinal cancer surgery operativeā€, ā€œenteral immunonutrition gastrointestinal cancer preoperativeā€, ā€œenteral immunonutrition gastrointestinal cancer perioperativeā€ e ā€œenteral immunonutrition gastrointestinal cancer postoperativeā€. Ao resultado da pesquisa foram aplicados os seguintes critĆ©rios de exclusĆ£o: - artigos que nĆ£o estivessem escritos em inglĆŖs ou em portuguĆŖs - artigos que nĆ£o iam de encontro ao assunto em questĆ£o AlĆ©m dos artigos, foram utilizadas revistas, livros cientĆ­ficos e alguns locais de internet. Resultados: VĆ”rios estudos demonstram que a imunonutriĆ§Ć£o Ć© superior Ć  nutriĆ§Ć£o padrĆ£o no que respeita Ć  restauraĆ§Ć£o da imunidade ajudando a modular a reaĆ§Ć£o inflamatĆ³ria, principalmente, em pacientes sujeitos a grandes cirurgias. A imunonutriĆ§Ć£o entĆ©rica, utilizando arginina, nucleĆ³tidos e glutamina, quando administrada no prĆ© e pĆ³s-operatĆ³rio Ć© de grande valor clĆ­nico, nomeadamente em pacientes desnutridos. No pĆ³s-operatĆ³rio, qualquer tipo de dieta imunomoduladora beneficia significativamente o paciente mas apenas em casos de desnutriĆ§Ć£o. Em pacientes, com cancro gastrointestinal, que recebem o suporte nutricional, a distribuiĆ§Ć£o de nutrientes por via entĆ©rica Ć© mais eficaz e mais econĆ³mica do que a via parentĆ©rica. ConclusƵes: Comparado com a nutriĆ§Ć£o entĆ©rica padrĆ£o, a imunonutriĆ§Ć£o por via entĆ©rica pode melhorar os mecanismos de defesa do organismo do doente com cancro gastrointestinal e modular a aĆ§Ć£o inflamatĆ³ria pĆ³s cirurgia. VĆ”rios estudos comprovam que a imunonutriĆ§Ć£o entĆ©rica prĆ©-operatĆ³ria, actua, reduzindo as complicaƧƵes, a morbilidade e a mortalidade no pĆ³s-operatĆ³rio, encurtando o tempo de internamento pĆ³s-cirurgia e assim reduzindo os custos na saĆŗde. Em suma, a sua utilizaĆ§Ć£o tem uma boa relaĆ§Ć£o custo-benefĆ­cio. Objective: To make a brief review of the literature about the importance of artificial nutrition, specifically, enteral immunonutrition in patients with gastrointestinal cancer, whether or not subjected to surgery. Methodology: It was performed a literature research in the database of the National Library of Medicine PubMed, Medline, and B-on, between April and October 2013, using the following terms: "Immunonutrition in gastrointestinal cancer surgery", "enteral immunonutrition gastrointestinal cancer surgery operative", "enteral immunonutrition gastrointestinal cancer preoperative ", "enteral immunonutrition gastrointestinal cancer perioperative" and "enteral immunonutrition gastrointestinal cancer postoperative." To the outcome of the research were applied the following exclusion criteria: - articles that were not written in English or Portuguese, - articles that were not related to the subject matter, In addition to the articles, were used journals, scientific books and some internet sites. Results: Several studies have shown that immunonutrition is better than the standard nutrition, helping to restore the immunity and modulating the inflammatory reaction namely in patients who have undergone major surgery. The enteric immunonutrition, using arginine, glutamine and nucleotides, administered preoperatively and postoperatively is a promising way of nutritional support particularly in malnourished patients. Postoperatively, any kind of immunomodulatory diet significantly benefits the patient but only in cases of malnutrition. In patients, with gastrointestinal cancer, receiving nutritional support, the enteral distribution of nutrients is more effective and economical than the parenteral route. Conclusions: Compared with standard enteral nutrition, enteral immunonutrition can improve the defense mechanisms of the patient with gastrointestinal cancer and modulate inflammatory reaction, after surgery. Several studies have shown that preoperative enteral immunonutrition improves postoperative outcome by reducing postoperative complications, morbidity and mortality in the postoperative period, shortening the hospital stay after surgery and thus reducing health costs. So, it as a good cost-benefit ratio.por
dc.identifier.urihttp://hdl.handle.net/10284/4272
dc.language.isoporpor
dc.publisher[s.n.]por
dc.subjectImunonutriĆ§Ć£opor
dc.subjectImunonutriĆ§Ć£o entĆ©ricapor
dc.subjectImunonutriĆ§Ć£o parentĆ©ricapor
dc.subjectNutriĆ§Ć£o padrĆ£opor
dc.subjectCancro gastrointestinalpor
dc.subjectComplicaƧƵes pĆ³s-operatĆ³riaspor
dc.subjectComplicaƧƵes infeciosaspor
dc.subjectImmunonutritionpor
dc.subjectEnteral immunonutritionpor
dc.subjectParenteral immunonutritionpor
dc.subjectStandard nutritionpor
dc.subjectGastrointestinal cancerpor
dc.subjectPostoperative complicationspor
dc.subjectInfectious complicationspor
dc.titleImunonutriĆ§Ć£o em doentes com cancro gastrointestinalpor
dc.typebachelor thesis
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typebachelorThesispor

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