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Sickle cell anemia and its impact on the oral cavity: integrative review

2025-10-14Recensão Acesso aberto
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datacite.subject.fosCiências Médicas
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorC. Leal, M. Fernanda
dc.contributor.authorGuimarães, Maria Inês
dc.contributor.authorNatbeth, Ambre
dc.contributor.authorLopes Cardoso, Inês
dc.date.accessioned2026-05-11T12:24:20Z
dc.date.available2026-05-11T12:24:20Z
dc.date.issued2025-10-14
dc.description.abstractIntroduction: Sickle cell anemia, a hereditary disease, results from a mutation in the β-globin coding gene that makes up hemoglobin, leading to the deformation of erythrocytes. Numerous oral manifestations result from this disease; however, some may not be specific. Objectives: This study’s objective is to recognize these clinical manifestations of the disease to be able to manage oral health in sickle cell anemia patients. Methods: this integrative review analyzes scientific literature on the impact of sickle cell anemia on oral cavity. A bibliographic search was performed in PubMed, ScienceDirect, CINAHL Plus (via EBSCO host), Web of Science and Google Scholar databases using several combined keywords. The research question was: “What is the impact of sickle cell anemia on the oral cavity and dental treatments?”. Results: By applying the inclusion and exclusion criteria, 11 articles were included in this review. Conclusions: Studies show that the most common oral manifestations in these patients are periodontal disease and caries, although this association is not well understood.eng
dc.description.abstractIntroduction: La drépanocytose, maladie héréditaire, résulte d’une mutation du gène codant pour la β-globine qui compose l’hémoglobine, entraînant la déformation des érythrocytes. De nombreuses manifestations bucco-dentaires résultent de cette maladie, mais certaines peuvent ne pas être spécifiques. Objectifs: Cette étude a pour but de reconnaître ces manifestations cliniques de la maladie pour pouvoir gérer la santé bucco-dentaire des patients atteints de drépanocytose. Méthodes: cette revue intégrative analyse la littérature scientifique sur l’impact de la drépanocytose sur la cavité buccale. Une recherche bibliographique a été effectuée dans les bases de données PubMed, ScienceDirect, CINAHL Plus (via EBSCO host), Web of Science et Google Scholar, en utilisant plusieurs mots-clés combinés. La question de recherche était la suivante: “Quel est l’impact de la drépanocytose sur la cavité buccale et les traitements dentaires? Résultats: En appliquant les critères d’inclusion et d’exclusion, 11 articles ont été inclus dans cette revue. Conclusions: Les études montrent que les manifestations bucco-dentaires les plus courantes chez ces patients sont les maladies parodontales et les caries, bien que cette association ne soit pas bien comprise.fra
dc.identifier.citationLeal, F., Guimarães, M. I., Natbeth, A., & Cardoso, I. L. (2025). Sickle cell anemia and its impact on the oral cavity: Integrative review. International Arab Journal of Dentistry, 16(2), Artigo 14. https://doi.org/10.70174/iajd.v16i2.1491
dc.identifier.doi10.70174/iajd.v16i2.1491
dc.identifier.issn22180885, 27094774
dc.identifier.urihttp://hdl.handle.net/10284/15416
dc.language.isoeng
dc.peerreviewedyes
dc.relation.hasversionhttps://e-journals.usj.edu.lb/iajd/vol16/iss2/14/
dc.rights.uriN/A
dc.subjectSickle cell disease
dc.subjectOral manifestations
dc.subjectDental treatments
dc.subjectOral health
dc.subjectCorrelation
dc.subjectDrépanocytose
dc.subjectManifestations buccales
dc.subjectTraitements dentaires
dc.subjectSanté bucco-dentaire
dc.subjectCorrélation
dc.titleSickle cell anemia and its impact on the oral cavity: integrative revieweng
dc.title.alternativeLa drepanocytose et son impact sur la cavite orale: revue integrativefra
dc.typereview
dspace.entity.typePublication
oaire.citation.endPage156
oaire.citation.issue2
oaire.citation.startPage145
oaire.citation.titleInternational Arab Journal of Dentistry
oaire.citation.volume16
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameC. Leal
person.familyNameGuimarães
person.familyNameLopes Cardoso
person.givenNameM. Fernanda
person.givenNameMaria Inês
person.givenNameInês
person.identifier.ciencia-id5416-2525-4C8B
person.identifier.ciencia-idF21F-16B4-3715
person.identifier.orcid0000-0002-0118-9007
person.identifier.orcid0000-0003-3687-7798
person.identifier.orcid0000-0002-0693-9831
person.identifier.ridM-7156-2013
person.identifier.scopus-author-id57213512502
person.identifier.scopus-author-id54973754300
relation.isAuthorOfPublicationcc0577f5-b02f-43ab-a135-b296ef6da8ac
relation.isAuthorOfPublication54d88a9d-f83b-4cce-8cc5-aac9ed7e701b
relation.isAuthorOfPublicationf39fa18f-2d23-4690-bfa2-f8ba53e40775
relation.isAuthorOfPublication.latestForDiscoveryf39fa18f-2d23-4690-bfa2-f8ba53e40775

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FCS (DCM)- Artigos em Revistas Científicas Internacionais com Arbitragem Científica