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Tratamento sistémico da psoríase: mudanças no padrão alimentar
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Advisor(s)
Abstract(s)
Psoríase é uma doença crónica da pele, de natureza autoimune, bastante comum e não
contagiosa. Embora a psoríase possa manifestar-se em qualquer idade, a maioria dos
casos ocorre entre os 15 e os 30 anos, sendo também comum entre os 50 e os 60 anos,
afetando cerca de 1% a 3% da população mundial. As manifestações epidérmicas,
características desta doença, podem surgir em qualquer parte do corpo, cujo agravamento
também pode estar associado com outras doenças como a diabetes, doença cardíaca e
depressão.
Esta doença apresenta uma etiologia que ainda não está completamente estabelecida, no
entanto, os fatores genéticos, imunológicos e ambientais são relevantes para o seu
desenvolvimento. O diagnóstico inclui a fisiopatologia, os fatores desencadeantes e a
classificação clínica. Posteriormente, surgem as terapias, incluindo-se tópica, oral,
biológica, terapia parenteral, fototerapia e fármacos.
A dieta, embora não seja considerada como uma terapia, exerce um papel preponderante
na prevenção, desenvolvimento e até recessão das manifestações epidérmicas inerentes a
esta doença. Por exemplo, o impacto na produção de citocinas no corpo, dependendo da
dieta adotada pelo doente, está relacionado com o tipo de alimentos ingeridos pelo
mesmo, uma vez que, o processo inflamatório pode ser regulado pelos hábitos alimentares
adotados. Face ao exposto, as mudanças nos padrões alimentares dos doentes psoriáticos
são extremamente relevantes.
Este trabalho teve como objetivo principal relacionar a importância dos alimentos como
fatores de prevenção, de manifestação e/ou agravamento da psoríase e ao mesmo tempo
viabilizar estratégias individuais para o aumento do consumo de alimentos saudáveis que
devam ser introduzidos nos padrões alimentares destes doentes. Para alcançar o propósito
deste trabalho, foi realizada uma pesquisa bibliográfica, entre setembro de 2020 e março
de 2021, de forma a reunir toda a informação necessária, visanto a pertinência e a
atualidade do tema em questão.
Após elaboração do trabalho e tendo em consideração os diferentes tipos e graus de
severidade da psoríase, fatores intervenientes e tipos de tratamentos recorrentes, concluiu-se que, até à data atual, nenhum estudo, abordou em concreto os alimentos benéficos e
termogénicos como fatores influentes desta patologia. Assim, este trabalho mostrou-se
relevante no âmbito da saúde pública, uma vez que, foi descrito a importância da
intervenção nutricional, incluindo alterações dos hábitos alimentares e/ou no aporte de
alguns nutrientes, como meio coadjuvante da terapêutica da psoríase. Também foram aqui
descritos, alguns alimentos prejudiciais, visando proporcionar uma maior amplitude de
informação para a contribuição do aumento da qualidade de vida dos doentes psoriáticos
e, consequentemente, na melhoria da saúde pública em geral.
Psoriasis is a chronic autoimmune skin disease, very common and not contagious. Although psoriasis can appear at any age, most cases occur between 15 and 30 years old, and it is also common between 50 and 60 years old, affecting about 1% to 3% of the population. The epidermal manifestations, characteristic of this disease, can appear in any part of the body, whose aggravation may also be associated with other diseases, including diabetes, heart disease and depression. This disease possess an etiology that is not yet fully established, however, genetic, immunological and environmental factors are relevant to its development. The diagnosis includes pathophysiology, triggering factors and clinical classification. Thereafter, therapies appear, including topical, oral, biological, parenteral therapy, phototherapy and drugs. Diet, although not considered as a therapy, plays a predominant role in the prevention, development and even resession of the epidermal manifestations related to this disease. For instance, the impact on the cytokines production in the body, depends on the diet adopted by each patient, being related with the type of food, since the inflammatory process can be regulated by the adopted eating habits. In view of the above, changes in the eating patterns of psoriatic patients are extremely relevant. This study aimed to relate the importance of foods as preventive factors, demonstration and /or worsening psoriasis and, at the same time, enable individual strategies to increase the consumption of healthy foods that should be introduced in the dietary patterns of these patients. To achieve the purpose of this work, a bibliographic research was carried out, between September 2020 and March 2021, in order to gather all the necessary information, aiming the pertinence and topicality of this main topic. After preparation of this work, and taking into account the different types, degrees of severity, intervening factors and types of recurring treatments in psoriasis, it was concluded that, until the present date, no study has addressed specifically the beneficial and thermogenic foods as influential factors of this pathology. Thus, this work proved to be relevant in the scope of public health, since, it described the importance of nutrition intervention, including changes in dietary habits and / or the intake of some nutrients, such as supporting the middle of psoriasis therapy. Some harmful foods were also described, aiming to provide a greater range of information for the contribution to the increase in life quality of psoriatic patients and, consequently, in the improvement of public health in general.
Psoriasis is a chronic autoimmune skin disease, very common and not contagious. Although psoriasis can appear at any age, most cases occur between 15 and 30 years old, and it is also common between 50 and 60 years old, affecting about 1% to 3% of the population. The epidermal manifestations, characteristic of this disease, can appear in any part of the body, whose aggravation may also be associated with other diseases, including diabetes, heart disease and depression. This disease possess an etiology that is not yet fully established, however, genetic, immunological and environmental factors are relevant to its development. The diagnosis includes pathophysiology, triggering factors and clinical classification. Thereafter, therapies appear, including topical, oral, biological, parenteral therapy, phototherapy and drugs. Diet, although not considered as a therapy, plays a predominant role in the prevention, development and even resession of the epidermal manifestations related to this disease. For instance, the impact on the cytokines production in the body, depends on the diet adopted by each patient, being related with the type of food, since the inflammatory process can be regulated by the adopted eating habits. In view of the above, changes in the eating patterns of psoriatic patients are extremely relevant. This study aimed to relate the importance of foods as preventive factors, demonstration and /or worsening psoriasis and, at the same time, enable individual strategies to increase the consumption of healthy foods that should be introduced in the dietary patterns of these patients. To achieve the purpose of this work, a bibliographic research was carried out, between September 2020 and March 2021, in order to gather all the necessary information, aiming the pertinence and topicality of this main topic. After preparation of this work, and taking into account the different types, degrees of severity, intervening factors and types of recurring treatments in psoriasis, it was concluded that, until the present date, no study has addressed specifically the beneficial and thermogenic foods as influential factors of this pathology. Thus, this work proved to be relevant in the scope of public health, since, it described the importance of nutrition intervention, including changes in dietary habits and / or the intake of some nutrients, such as supporting the middle of psoriasis therapy. Some harmful foods were also described, aiming to provide a greater range of information for the contribution to the increase in life quality of psoriatic patients and, consequently, in the improvement of public health in general.
Description
Keywords
Psoríase Manifestações clínicas Fatores genéticos Fatores imunológicos Fatores ambientais Dieta alimentar Alimentos benéficos Alimentos termogénicos/prejudiciais Psoriasis Clinical manifestations Genetic factors Immunological factors Environmental factors Diet Beneficial foods Thermogenic /harmful foods